背景介绍 Bromodomains function as acetyl-lysine binding domains, and bromodomain/ acetyl-lysine recognition can regulate histone modification, DNA replications, chromatin remodeling, and gene transcription. 产品介绍 The Bromodomain Non-acetylated Ligand 1 is negative control for the BET Bromodomain Ligand, Cat. #33000. It is a peptide histone H4 (1-21) containing a C-terminal GG linker, followed by a biotinylated Lys. This peptide is suitable for use as a ligand for several bromodomains including members of the BET bromodomain family: BRD2, BRD3, BRD4, and BRDT.