背景介绍 Histone acetyltransferase (HAT) p300/CBP catalyses the acetylation of this N-terminal tail of free histone H4 at Lys5, 8, 12, 16. Lys8 is thought to be the preferred acetylation site in H4. A number of methyltransferases also modify this region of the histone. 产品介绍 A peptide substrate for Histone 4 R3 methyltransferases. The peptide corresponds to amino acid residues 1-21 of histone H4.