背景介绍 As part of the MLL1/MLL complex, involved in the methylation of histone H3 at Lys-4, particularly trimethylation. Histone H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 Lys-4 methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. 产品介绍 Human dpy-30 homolog, or DPY30, GenBank Accession No. NM_032574, a.a. 2 - 99 (end) with N-terminal His-tag, MW= 12 kDa, expressed in an E. coli expression system.