背景介绍 CD73, also known as Ecto-5'-nucleotidase (5'-NT), promotes tumor growth and progression by degrading AMP into adenosine. CD73-generated adenosine blocks T-cell immuno-surveillance, resulting in an immunosuppressed and pro-angiogenic niche within the tumor microenvironment. 产品介绍 The CD73 Inhibitor Screening Assay Kit is designed to measure CD73 activity for screening and profiling applications. The CD73 assay kit comes in a convenient 384-well format, with purified recombinant CD73 enzyme, AMP, CD73 assay buffer, and Colorimetric detection reagent for 384 enzyme reactions.