背景介绍 Furin is a member of the proprotein convertase (PC) family, which belongs to the subtilisin superfamily of serine protease. This protease is thought to cleave and activate more than 150 mammalian, viral and bacterial substrates. Among them are viral envelope glycoproteins and bacterial toxins, as well as cellular factors that can promote tumor development and growth. Cleavage of the SARS coronavirus spike glycoprotein by Furin is a critical step in viral fusion and entry, making furin a potential target for SARS-CoV-2 therapy. 产品介绍 The Furin Protease Assay Kit is designed to measure Furin Protease activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.