背景介绍 CD38, a differentiation antigen of B lymphocytes, is a type II integral membrane protein that functions as an ADP-ribosyl cyclase and nicotinamide adenine dinucleotide (NAD) glycohydrolase. The major enzymatic activity of CD38 is the hydrolysis of NAD. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in various cells, including pancreatic ÃŸ cells. CD38 is a prognostic biomarker for acute B lymphoblastic leukemia. 产品介绍 The Dog CD38 Inhibitor Screening Assay Kit (Hydrolase Activity) is designed to measure the glycohydrolase activity of canine CD38 for screening and profiling applications.