背景介绍 RIPK1 is a member of the receptor-interacting protein kinase (RIP) family. It plays an important role in cell survival as well as cell death including apoptosis and necroptosis. RIPK1 is highly expressed in Alzheimer's disease (AD) brains. Importantly, it was shown that inhibition of RIPK1 results in decrease of amyloid and inflammation levels as well as accelerating amyloid beta peptide (Aβ) degradation by microglia in vitro. 产品介绍 The RIPK1 Kinase Assay Kit is designed to measure RIPK1 kinase activity for screening and profiling applications using ADP-Glo® Kinase Assay as a detection reagent.