背景介绍 PIM kinases (PIM1, PIM2 and PIM3) are a family of serine/threonine protein kinases that play crucial roles in cell survival, proliferation, and drug resistance. PIM kinases are overexpressed in several tumors and promote growth and survival of malignant cells through cell cycle regulation and/or inhibition of apoptosis. Recently, PIM kinases were identified as a potential therapeutic target for precision medicine of advanced cancer. 产品介绍 The PIM1 Assay Kit is designed to measure PIM1 activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.