背景介绍 Staphylococcal Sortase A is a bacterial transpeptidase that covalently attaches proteins to the bacterial cell wall by cleaving between threonine and glycine at an LPXTG recognition motif. It catalyzes the formation of an amide bond between the carboxyl-group of threonine and the amino-group of the cell-wall peptidoglycan, which is an essential procedure for pathogens to sustain infection. Thus, Sortase A has potential as an anti-infective therapy target, especially for antibiotic-resistant bacteria. 产品介绍 The Sortase A Assay Kit is designed to measure Sortase A activity for screening and profiling applications.