背景介绍 Cathepsin F is a lysosomal cysteine protease that belongs to the papain-like superfamily. It is secreted by macrophages and is thought to play a role in processing and loading peptides into MHC complexes. Cathepsin F is also expressed in atherosclerotic lesions, where it degrades ApoB-100, triggering LDL aggregation. It has been implicated in tumor invasion and metastasis, inducing apoptosis of gastric cancer cells, and mutations in cathepsin F have been linked to Alzheimer's disease and Type B Kuf's disease. 产品介绍 The Cathepsin F Inhibitor Screening Assay Kit is designed to measure the protease activity of Cathepsin F for screening and profiling applications.