背景介绍 MMP13 (matrix metalloproteinase 13), also known as collagenase 3, is a member of the matrix metalloproteinase (MMP) family involved in the degradation of the extracellular matrix. MMP13 primarily cleaves type II collagen, and it is expressed in the skeleton where it plays a role in restructuring the collagen matrix for bone mineralization and cartilage turnover. MMP13 is also overexpressed in rheumatoid arthritis, osteoarthritis, and many human carcinomas, suggesting its potential as a therapeutic target. 产品介绍 The Fluorogenic MMP13 Assay Kit is designed to measure MMP13 activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.