背景介绍
Acetylation of histone H3 is associated with active gene transcription. Acetylation at H3K18 and H3K24 favors methylation at H3R17me by CARM1/PRMT4. SIRT7 is a chromatin-associated H3K18Ac-specific deacetylase. Studies show a significant correlation between low expression of H3K18ac and better prognosis of patients with oesophageal squamous cell carcinoma.
产品介绍
Polyclonal antibody raised in rabbit against histone H3 containing the acetylated lysine 18 (H3K18ac), using a KLH-conjugated synthetic peptide