背景介绍 Set9 (UniProtKB/Swiss-Prot entry Q8WTS6) is a histone methyltransferase which specifically methylates lysine 4 of histone H3 being a specific tag for epigenetic transcriptional activation. Further, methylation of histone H3K4 by Set9 precludes deacetylation of H3 by the NuRD complex and impairs Suv39h1-mediated methylation of H3K9. Set9 also methylates the tumor suppressor p53 at lysine 372, thereby enhancing its stability. It contains a SET domain but lacks the pre- and post-SET domains. 产品介绍 Polyclonal antibody raised in rabbit against human Set9 (SET domain containing (lysine methyltransferase) 9), using a recombinant protein.