背景介绍
Myotonic Dystrophy Kinase-Related cdc42-binding kinase beta (MRCKβ) belongs to the DMPK subfamily (1). The myotonic dystrophy kinase-related kinases and myotonic dystrophy kinase-related Cdc42 binding kinase (MRCK) are effectors of RhoA and Cdc42, respectively, where they are involved in actin cytoskeletal reorganization and neurite outgrowth (2). Effects of the repeat expansion on the DMPK gene may be responsible for muscle and heart features of Myotonic Dystrophy.
产品介绍
Recombinant human Myotonic Dystrophy Kinase-Related cdc42-binding kinase beta (MRCKβ), a.a. 1-473, with N-terminal GST-tag, expressed by Sf9 insect cells via a baculovirus expression system.