背景介绍 RSK1 is a member of the RSK (ribosomal S6 kinase) family that are growth factor-regulated serine/threonine kinases. RSK1 contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. RSK1 encodes a predicted 735-amino acid protein containing 2 distinct consensus ATP-binding site sequences. RSK1 transcript is present in lymphocytes, skeletal muscle, liver, and adipose tissue (1). RSKs are implicated in the activation of the mitogen-activated kinase (MAPK) cascade and the stimulation of cell proliferation and differentiation (2). 产品介绍 Recombinant human RSK1 (ribosomal S6 kinase 1), also known as MAPKAPK1A, S6K-β1, and RPS6KA1 Genbank Accession #NM_002953, full length, with an N-terminal GST-tag, MW = 108 kDa, expressed in Sf9 cells via a baculovirus expression system.