背景介绍 RSK4 is a member of the 90- kDa ribosomal S6 kinase family which are important components of growth factor mediated stimulation of cellular proliferation, survival and differentiation. RSK4 is activated via coordinated phosphorylation by ERK and 3-phosphoinositide-dependent protein kinase-1 (PDK1) (1). RSK4 is often associated with contiguous gene syndromes consisting of X-linked deafness type 3 (DFN3), mental retardation (MRX) and choroideremia (CHM). RSK4 is most abundantly expressed in the brain and kidney (2). 产品介绍 Recombinant human RSK4 (ribosomal S6 kinase 4), full length, with N-terminal GST-tag, expressed by Sf9 insect cells via a baculovirus expression system.