背景介绍 LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family. LATS2 interacts with a negative regulator of p53 and function in a positive feedback loop with p53 that responds to cytoskeleton damage and this interaction provokes centrosome/mitotic apparatus dysfunction (1). LATS2 plays an essential role in the maintenance of mitotic fidelity and genomic integrity (2). 产品介绍 Human LATS2 protein with N-terminal GST-Tag, GenBank Accession No. NM_014572, a.a 480-1088, expressed in an Sf9 expression system. MW = 110 kDa.