背景介绍 KAT5 or K (lysine) acetyltransferase 5 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs). KAT5 was originally isolated as an HIV-1 TAT-interactive protein that plays an important role in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins (1). KAT5 protein is a histone acetylase that is involved in DNA repair and apoptosis and plays an important role in signal transduction. KAT5 acts as a cofactor of TAT that is involved in the regulation of HIV gene expression. KAT5 is also a co-regulator of transcription factors that either promote or suppress tumorigenesis (2). 产品介绍 Full-length recombinant Human KAT5 (TIP60) protein also known as cPLA2 ESA1 HTATIP, HTATIP1, PLIP, and TIP. Genbank Accession NM_006388, with an N-terminal GST tag expressed by baculovirus in Sf9 insect cells. MW = 88kDa.