背景介绍 Unlike TSA, Sirtinol does not inhibit class I and class II HDACs, indicating that it is a selective sirtuin inhibitor. The downregulation of SIRT1/2 expression plays an important role in the regulation of breast cancer apoptosis; thus, SIRT1/2 may be a novel molecular target for cancer therapy. 产品介绍 Cell-permeable, selective sirtuin inhibitor that has no effect on HDAC1 activity. Significantly decreases growth and viability of PCa and HEK293T cells in vitro.