背景介绍 Wnt-C59 prevents palmitoylation of Wnt proteins by Porcupine (a membrane-bound O-acyltransferase), thereby blocking Wnt protein secretion and activity, similar to Wnt inhibitors IWP-2, IWP-3 and IWP-4. But Wnt-C59 is more potent and selective, and has better chemical/physical properties, and is more suitable for in vitro/in vivo studies. 产品介绍 Wnt-C59 is a very potent and highly selective Wnt signaling antagonist with an IC50 ~ 74 pM in the Wnt signaling reporter assay.