背景介绍 NET is a monoamine transporter responsible for the sodium-chloride (Na+/Cl¯)-dependent reuptake of extracellular norepinephrine (NE), also known as noradrenaline. NET can also reuptake extracellular dopamine (DA). The reuptake of these two neurotransmitters is essential in regulating concentrations in the synaptic cleft. NETs, along with the other monoamine transporters, play a key role in depression and neurodegenerative diseases (NDD) such as Alzheimer's and Parkinson's disease. NET is the target of many antidepressants and recreational drugs. In addition, an overabundance of NET is associated with ADHD. 产品介绍 Recombinant CHOK1 cell line expressing human norepinephrine transporter (NET), Genbank accession number NM_001043.