背景介绍 A chronic pain mediator, NGF (Nerve Growth Factor) binds to TrkA resulting in activation of the downstream signaling pathway linked to pro-nociception; therefore, targeting the kinase activity of TrkA and the interaction between NGF/TrkA have been attractive tools in pain management research. In addition to control of chronic pain, a recent clinical success has proven that inhibition of TrkA kinase would be a promising anti-cancer strategy. 产品介绍 Recombinant HEK-293 cells expressing firefly luciferase gene under the control of Serum Response Elements (SRE) with constitutive expression of human TrkA (Tropomyosin receptor kinase A; NTRK1; ref. seq. NM_002529.3).